BS 49 93 Tryptophan Anchors in Transmembrane Peptides Roger E. Koeppe II, J. Antoinette Killian, Denise V. Greathouse, and Olaf S. Andersen Abstract Geometric considerations prescribe that embedded proteins may be regarded as “defects” in lipid bilayers (unless there is “perfect” structural matching). A critical accumulation of such defects could mandate a lipid phase tra